Thermo Fisher Scientific Inc. today announced the release of a new Raman spectroscopic analyzer for process monitoring for a variety of applications, including biopharmaceutical manufacturing. The Thermo Scientific Ramina Process Analyzer offers non-destructive and continuous analysis without the need for sample preparation, with rapid system setup and deployment in as little as 15 minutes to generate spectral data on target analytes within seconds.

This easy-to-use system is designed to eliminate the complexity of performing Raman spectroscopy measurements, making the technique accessible to all levels of user experience while maintaining high precision and accuracy. The compact system utilizes a range of patented probes to maximize the speed and sensitivity of results, enabling fully automated in situ measurements to calculate concentrations in a reaction vessel.

The Ramina Process Analyzer offers a rapid and easy-to-use alternative to offline manual or automated wet chemistry testing, and is simpler to install and use compared to traditional Raman process monitoring systems. Ramina comes with everything the user needs to start collecting data, including a Raman spectrometer and fiber optic probe, as well as a portable monitor, mouse, keyboard and laser safety goggles. Factory calibration ensures the Ramina system is ready to use without delay, and its solid-state construction offers long-term stability, meaning users can enjoy continuous, highly accurate measurements without frequent calibration. Users can also use multiple systems in parallel to test different reaction vessels simultaneously, or combine a number of probes in one vessel.

Chloe Hansen-Toone, vice president and general manager for field and safety instruments at Thermo Fisher, commented: “We are excited to launch the Ramina Process Analyzer, which offers an almost effortless method of performing precise in situ Raman measurements, enabling customers to generate real-time data where and when they need it. The compact and portable design of this analyzer, as well as its user-friendly operation, will help to reduce time-to-results without the burden of taking up too much valuable laboratory space.”

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